翻訳と辞書 Words near each other ・ BCL Molecular ・ BCL Springs ・ Bcl-2 ・ Bcl-2 family ・ Bcl-2 homologous antagonist killer ・ Bcl-2-associated death promoter ・ Bcl-2-associated X protein ・ Bcl-2-interacting killer ・ BCL-6 corepressor ・ Bcl-x interacting domain ・ Bcl-xL ・ BCL10 ・ BCL11A ・ BCL11B ・ BCL2-like 1 (gene) ・ BCL2-related protein A1 ・ BCL2L10 ・ BCL2L11 ・ BCL2L12 ・ BCL2L13 ・ BCL2L14 ・ BCL2L2 ・ BCL3 ・ BCL6 ・ BCL6B ・ BCL9 ・ BCLAF1 ・ BCLUW Community School District ・ BCM ・ BCM Classification Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク BCL2-related protein A1 ： ウィキペディア英語版 BCL2-related protein A1 Bcl-2-related protein A1 is a protein that in humans is encoded by the ''BCL2A1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=597 )〕 == Function == This gene encodes a member of the bcl2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.〔 In melanocytic cells BCL2A1 gene expression may be regulated by MITF. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「BCL2-related protein A1」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.